Control of rabbit dura mater optical properties with osmotical liquids

Lei Yao; Haiying Cheng; Qingming Luo; Wei Zhang; Shaoqun Zeng; Valery V. Tuchin

doi:10.1117/12.462541

12 April 2002 Control of rabbit dura mater optical properties with osmotical liquids

Lei Yao, Haiying Cheng, Qingming Luo, Wei Zhang, Shaoqun Zeng, Valery V. Tuchin

Author Affiliations +

Proceedings Volume 4536, International Workshop on Photonics and Imaging in Biology and Medicine; (2002) https://doi.org/10.1117/12.462541
Event: International Workshop on Photonics and Imaging in Biology and Medicine, 2001, Wuhan, China

Abstract

An experimental study of controlling the optical properties of in vitro and in vivo rabbit dura mater with administration of osmotical agents, 40% glucose solution and glycerol, using video camera and spectrometer was presented. The preliminary results of experimental study of influence of osmotical liquids (glucose solutions, glycerol) on transmittance (in vitro) and reflectance (in vivo) spectra of rabbit dura mater were reported. The significant decreasing of the reflectance and increasing of the transmittance of dura mater under action of osmotical solutions were demonstrated. Experiments showed that administration of osmolytes to dura mater allowed for effective and temporary control of its optical characteristics, which made dura mater more transparent, increased the ability of light penetrating the tissue, and consequently improved the optical imaging depth. It is a significant study, which can improve penetration of optical imaging of cerebral function and acquire more information of the deep brain tissue.

Citation Download Citation

Lei Yao, Haiying Cheng, Qingming Luo, Wei Zhang, Shaoqun Zeng, and Valery V. Tuchin "Control of rabbit dura mater optical properties with osmotical liquids", Proc. SPIE 4536, International Workshop on Photonics and Imaging in Biology and Medicine, (12 April 2002); https://doi.org/10.1117/12.462541

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