Speckle contrast techniques in the study of tissue thermal modification and denaturation

Dmitry N. Agafonov; Liana V. Kuznetsova; Dmitry A. Zimnyakov; Alexander P. Sviridov; Alexander I. Omelchenko

doi:10.1117/12.469005

31 May 2002 Speckle contrast techniques in the study of tissue thermal modification and denaturation

Dmitry N. Agafonov, Liana V. Kuznetsova, Dmitry A. Zimnyakov, Alexander P. Sviridov, Alexander I. Omelchenko

Proceedings Volume 4705, Saratov Fall Meeting 2001: Coherent Optics of Ordered and Random Media II; (2002) https://doi.org/10.1117/12.469005
Event: Saratov Fall Meeting 2001, 2001, Saratov, Russian Federation

Abstract

Results of the contrast analysis of time-averaged dynamic speckle patterns in application to monitoring of the structure modification of the thermally treated collagenous tissue such as cartilage are presented. The modification presumably induced by the bound to free water phase transition in the matrix of the treated tissue cause the specific feature of evolution of the time-averaged speckle contrast with the change of the current temperature of modified collagen tissue. This evolution appears as hysteresis associated with irreversible changes in tissue structure.

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Dmitry N. Agafonov, Liana V. Kuznetsova, Dmitry A. Zimnyakov, Alexander P. Sviridov, and Alexander I. Omelchenko "Speckle contrast techniques in the study of tissue thermal modification and denaturation", Proc. SPIE 4705, Saratov Fall Meeting 2001: Coherent Optics of Ordered and Random Media II, (31 May 2002); https://doi.org/10.1117/12.469005

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