Chemomertical analysis of endometrial tissue fluorescence spectra

Aurelija Vaitkuviene; E. Auksorius; D. Fuchs; V. Gavriushin

doi:10.1117/12.486602

15 October 2002 Chemomertical analysis of endometrial tissue fluorescence spectra

Aurelija Vaitkuviene, E. Auksorius, D. Fuchs, V. Gavriushin

Proceedings Volume 4903, Laser Florence 2001: A Window on the Laser Medicine World; (2002) https://doi.org/10.1117/12.486602
Event: Laser Florence 2001: a Window on the Laser Medicine World, 2001, Florence, Italy

Abstract

An effort has been made to detect neopterin spectrum in fluorescence of premalignant endometrial tissue and to estimate the number of fluorophores naturally existing in the tissue with fluorescence present above the noise level. Endometrial Tissue fluorescence was measured in vitro by excitation with the third harmonic of Nd YAG laser. Multivariate curve resolution was used for testing neopterin presence in endometrial tissue. Fluorescence spectra ofneopterin was measured and used as a target spectrum for testing. Seven factors -fluorescence ofnatural fluorophores ofendometrial tissue were found to be present above the noise level in the overall autofluorescence. Neopterin concentration may be too low in endometrial tissue to make its fluorescence above the noise level because neopterin spectrum was not found to be among the spectra resolved by multivariate curve resolution. An intensity increase in the neopterin spectrum spectral region in hyperplastic endometrial samples might be associated with neopterin concentration increase.

Citation Download Citation

Aurelija Vaitkuviene, E. Auksorius, D. Fuchs, and V. Gavriushin "Chemomertical analysis of endometrial tissue fluorescence spectra", Proc. SPIE 4903, Laser Florence 2001: A Window on the Laser Medicine World, (15 October 2002); https://doi.org/10.1117/12.486602

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available