Cellular automata for exploring gene regulation in Drosophila segmentation

Matthew J. Berryman; Andrew G. Allison; Derek Abbott

doi:10.1117/12.522203

29 March 2004 Cellular automata for exploring gene regulation in Drosophila segmentation

Matthew J. Berryman, Andrew G. Allison, Derek Abbott

Proceedings Volume 5275, BioMEMS and Nanotechnology; (2004) https://doi.org/10.1117/12.522203
Event: Microelectronics, MEMS, and Nanotechnology, 2003, Perth, Australia

Abstract

In this paper we present a 3D cellular automaton for exploring gene interactions in segmentation of Drosophila larvae. Beginning with the expression levels of maternally expressed genes such as bicoid, our simple model successfully produces the distinctive expression pattern of the even-skipped gene in the developing larvae. This work highlights how complex gene interactions in developing organism can nonetheless be accurately modeled using simple rules.

Citation Download Citation

Matthew J. Berryman, Andrew G. Allison, and Derek Abbott "Cellular automata for exploring gene regulation in Drosophila segmentation", Proc. SPIE 5275, BioMEMS and Nanotechnology, (29 March 2004); https://doi.org/10.1117/12.522203

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