Tissue and cell-based biomimetic templates generated via dip-pen nanolithography

Albena Ivanisevic

doi:10.1117/12.530317

1 July 2004 Tissue and cell-based biomimetic templates generated via dip-pen nanolithography

Albena Ivanisevic

Proceedings Volume 5322, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues II; (2004) https://doi.org/10.1117/12.530317
Event: Biomedical Optics 2004, 2004, San Jose, CA, United States

Abstract

The identification, fabrication and evaluation of biomimetic templates hold great potential for a variety of applications. The generation of templates on these substrates is achieved using an appropriately modified atomic force microscope (AFM) tip. The fabrication process of tissue and cell based templates reported in this paper is accomplished using Dip-Pen Nanolithography. This report identifies critical parameters necessary for the patterning process: initial surface quality, temperature and humidity conditions. The results of this proof of concept experiment can be utilized in future in vitro and in vivo studies to test the templates bio-compatibility and specificity.

Citation Download Citation

Albena Ivanisevic "Tissue and cell-based biomimetic templates generated via dip-pen nanolithography", Proc. SPIE 5322, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues II, (1 July 2004); https://doi.org/10.1117/12.530317

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