A realistic coupled nonlinear artificial ECG, BP, and respiratory signal generator for assessing noise performance of biomedical signal processing algorithms

Gari D. Clifford; Patrick E. McSharry

doi:10.1117/12.544525

25 May 2004 A realistic coupled nonlinear artificial ECG, BP, and respiratory signal generator for assessing noise performance of biomedical signal processing algorithms

Gari D. Clifford, Patrick E. McSharry

Author Affiliations +

Proceedings Volume 5467, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II; (2004) https://doi.org/10.1117/12.544525
Event: Second International Symposium on Fluctuations and Noise, 2004, Maspalomas, Gran Canaria Island, Spain

Abstract

Extensions to a previously published nonlinear model for generating realistic artificial electrocardiograms to include blood pressure and respiratory signals are presented. The model accurately reproduces many of the important clinical qualities of these signals such as QT dispersion, realistic beat to beat variability in timing and morphology and pulse transit time. The advantage of this artificial model is that the signal is completely known (and therefore its clinical descriptors can be specified exactly) and contains no noise. Artifact and noise can therefore be added in a quantifiable and controlled manner in order to test relevant biomedical signal processing algorithms. Application examples using Independent Component Analysis to remove artifacts are presented.

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Gari D. Clifford and Patrick E. McSharry "A realistic coupled nonlinear artificial ECG, BP, and respiratory signal generator for assessing noise performance of biomedical signal processing algorithms", Proc. SPIE 5467, Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II, (25 May 2004); https://doi.org/10.1117/12.544525

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