Shape deformations of giant unilamellar vesicles with a laser tweezer array

Wolfgang Losert; Cory Poole; Peter Bradford; Doug English

doi:10.1117/12.557589

18 October 2004 Shape deformations of giant unilamellar vesicles with a laser tweezer array

Wolfgang Losert, Cory Poole, Peter Bradford, Doug English

Proceedings Volume 5514, Optical Trapping and Optical Micromanipulation; (2004) https://doi.org/10.1117/12.557589
Event: Optical Science and Technology, the SPIE 49th Annual Meeting, 2004, Denver, Colorado, United States

Abstract

Vesicles are phospholipid bilayers that form a surface enclosing a volume of water or solution. They are of importance as model systems to study cells, as well as having practical applications such as containers for performing nanochemistry and facilitating drug delivery. Their properties have been studied for decades. Using a holographic laser tweezer array (LTA), which converts a single laser beam into many laser tweezer points, we stretch the vesicles in controlled ways from several points at once, measuring each force applied. Here, we present data on shape deformations of simple, spherical vesicles and on membrane fracture.

Citation Download Citation

Wolfgang Losert, Cory Poole, Peter Bradford, and Doug English "Shape deformations of giant unilamellar vesicles with a laser tweezer array", Proc. SPIE 5514, Optical Trapping and Optical Micromanipulation, (18 October 2004); https://doi.org/10.1117/12.557589

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