Evaluation of quantum dots for photodynamic therapy

Smita Dayal; Robert Krolicki; Clemens Burda

doi:10.1117/12.591989

28 April 2005 Evaluation of quantum dots for photodynamic therapy (Invited Paper)

Smita Dayal, Robert Krolicki, Clemens Burda

Proceedings Volume 5705, Nanobiophotonics and Biomedical Applications II; (2005) https://doi.org/10.1117/12.591989
Event: SPIE BiOS, 2005, San Jose, CA, United States

Abstract

Photodynamic therapy (PDT) is an emerging therapy for cancer treatment that shows the greater selectivity towards the malignant cells. Semiconductor nanoparticles are a novel class of photosensitizers with properties that are not easily available with conventional PDT reagents. Their potential properties such as improved luminescence, resistance to photobleaching, and the possibility to modify the surface chemically make them suitable candidates for PDT. In this report, we discuss the synthesis of ternary CdSe_1-x Tex nanoparticles along with well known CdSe QDs and their potential in generating the singlet oxygen state by Foerster Resonance Energy Transfer (FRET) to a PDT reagent or by direct triplet-triplet energy transfer to molecular oxygen.

Citation Download Citation

Smita Dayal, Robert Krolicki, and Clemens Burda "Evaluation of quantum dots for photodynamic therapy (Invited Paper)", Proc. SPIE 5705, Nanobiophotonics and Biomedical Applications II, (28 April 2005); https://doi.org/10.1117/12.591989

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