Interstitial Doppler optical coherence tomography

Victor X. D. Yang; Linda Mao; Nigel Munce; Beau Standish; Norman E. Marcon M.D.; Walter Kucharczyk; Brian C. Wilson; I. Alex Vitkin

doi:10.1117/12.623868

23 May 2005 Interstitial Doppler optical coherence tomography

Victor X. D. Yang, Linda Mao, Nigel Munce, Beau Standish, Norman E. Marcon M.D., Walter Kucharczyk, Brian C. Wilson, I. Alex Vitkin

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Proceedings Volume 5855, 17th International Conference on Optical Fibre Sensors; (2005) https://doi.org/10.1117/12.623868
Event: 17th International Conference on Optical Fibre Sensors, 2005, Bruges, Belgium

Abstract

Doppler optical coherence tomography (OCT) can image tissue structure and blood flow at micrometer-scale resolution, with limited imaging penetration depth. We report a novel linear-scanning needle-based Doppler OCT system using angle-polished gradient-index or ball-lensed fibers. A prototype system using a 19-guage (diameter ~0.9 mm) echo-genic needle is constructed and demonstrates in vivo imaging of bidirectional blood flow in rat leg and abdominal cavity. To our knowledge this is the first demonstration of Doppler OCT through a needle probe in interstitial applications to visualize deeply situated microcirculation.

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Victor X. D. Yang, Linda Mao, Nigel Munce, Beau Standish, Norman E. Marcon M.D., Walter Kucharczyk, Brian C. Wilson, and I. Alex Vitkin "Interstitial Doppler optical coherence tomography", Proc. SPIE 5855, 17th International Conference on Optical Fibre Sensors, (23 May 2005); https://doi.org/10.1117/12.623868

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KEYWORDS

Optical coherence tomography

Optical fibers

Polishing

Doppler tomography

Blood circulation

In vivo imaging

Tissues

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