Quantifiability and image quality in noncontact fluorescence tomography

Ralf B. Schulz; Joerg Peter; Wolfhard Semmler; Cosimo D'Andrea; Gianluca Valentini; Rinaldo Cubeddu

doi:10.1117/12.632855

26 October 2005 Quantifiability and image quality in noncontact fluorescence tomography

Ralf B. Schulz, Joerg Peter, Wolfhard Semmler, Cosimo D'Andrea, Gianluca Valentini, Rinaldo Cubeddu

Proceedings Volume 5859, Photon Migration and Diffuse-Light Imaging II; 58590Z (2005) https://doi.org/10.1117/12.632855
Event: European Conferences on Biomedical Optics 2005, 2005, Munich, Germany

Abstract

Non-contact detection schemes for optical or fluorescence tomography offer several advantages compared to classic approaches, most importantly the ability to obtain images with a CCD in the absence of a matching fluid or fiber optics. This allows the acquisition of high density datasets, as well as simplified experimental procedures. Herein we create a unified framework for contact and non-contact detection procedures and present experimental results that show the ability of the non-contact method to quantify the concentration of fluorochromes hidden in turbid media as well as the improvement in image quality between conventional and non-contact detection.

Citation Download Citation

Ralf B. Schulz, Joerg Peter, Wolfhard Semmler, Cosimo D'Andrea, Gianluca Valentini, and Rinaldo Cubeddu "Quantifiability and image quality in noncontact fluorescence tomography", Proc. SPIE 5859, Photon Migration and Diffuse-Light Imaging II, 58590Z (26 October 2005); https://doi.org/10.1117/12.632855

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