Interferometric tissue characterization: III: calibration

Marija Strojnik; Gonzalo Paez

doi:10.1117/12.621261

15 September 2005 Interferometric tissue characterization: III: calibration

Marija Strojnik, Gonzalo Paez

Proceedings Volume 5883, Infrared Spaceborne Remote Sensing 2005; 58830V (2005) https://doi.org/10.1117/12.621261
Event: Optics and Photonics 2005, 2005, San Diego, California, United States

Abstract

We described a new method to determine tissue density using a modified interferometric scattering experiment.¹ The most critical aspect of the tissue characterization problem is calibration of experimental measurements. During the calibration step, the absorption and scattering indices βa and βsc are determined as a function of concentration, for each material or tissue of interest, using a set of containers to vary travel distance D. It is assumed that linear scattering coefficient, ksc (absorption coefficient, αa), is proportional to number of scattering particles per unit volume, or particle concentration, c, in [ml/l]. Attenuation is proportional to concentration of scattering/absorption centers and sample length. The calibration method relates the fringe irradiance (power modulation in one interferometer arm) with the sample concentration under controlled conditions.

Citation Download Citation

Marija Strojnik and Gonzalo Paez "Interferometric tissue characterization: III: calibration", Proc. SPIE 5883, Infrared Spaceborne Remote Sensing 2005, 58830V (15 September 2005); https://doi.org/10.1117/12.621261

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