Combined photothermal-photometric method for the determination of tissue optical properties

E. S. R. Fonseca D.D.S.; M. E. P. de Jesus

doi:10.1117/12.644120

1 March 2006 Combined photothermal-photometric method for the determination of tissue optical properties

E. S. R. Fonseca D.D.S., M. E. P. de Jesus

Proceedings Volume 6084, Optical Interactions with Tissue and Cells XVII; 60840N (2006) https://doi.org/10.1117/12.644120
Event: SPIE BiOS, 2006, San Jose, California, United States

Abstract

A novel method for measuring the optical properties of highly absorbing and scattering biological media is described. The method combines frequency-domain photothermal radiometry (FD-PTR) with spatially resolved diffuse reflectance (SR-DR) techniques aimed at improving sensitivity on the determination of both scattering and absorption coefficients. Simulation results with Monte-Carlo and Diffusion Theory approaches that assess the scope and feasibility of the method are presented. An optical fiber probe for SR-DR measurements was constructed for operations at small source-detector separations and an FD-PTR system was adapted for quasi-simultaneous operation with the probe. Several experiments on epoxy phantoms that illustrate the validity and potential of the method are presented.

Citation Download Citation

E. S. R. Fonseca D.D.S. and M. E. P. de Jesus "Combined photothermal-photometric method for the determination of tissue optical properties", Proc. SPIE 6084, Optical Interactions with Tissue and Cells XVII, 60840N (1 March 2006); https://doi.org/10.1117/12.644120

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