Enzyme electrodes immobilized on hetero-structured metallic nanowire array for glucose sensing

Hargsoon Yoon; Devesh Deshpande; Ritesh R. Chintakuntla; Vijay K. Varadan

doi:10.1117/12.695223

14 December 2006 Enzyme electrodes immobilized on hetero-structured metallic nanowire array for glucose sensing

Hargsoon Yoon, Devesh Deshpande, Ritesh R. Chintakuntla, Vijay K. Varadan

Proceedings Volume 6416, Biomedical Applications of Micro- and Nanoengineering III; 641608 (2006) https://doi.org/10.1117/12.695223
Event: SPIE Smart Materials, Nano- and Micro-Smart Systems, 2006, Adelaide, Australia

Abstract

The fabrication of hetero-structured vertically aligned nanowire arrays and enzyme immobilization on their surface is presented for a glucose sensor with high sensitivity. Hetero-structured nanowires of gold and platinum are fabricated by hybrid polycarbonate membrane assembly and electrochemical deposition processes and glucose oxidase are attached on their surface by covalent immobilization. Platinum and gold hetero-structured nanoelectrodes with enzyme are evaluated to detect hydrogen peroxide produced in the enzyme reaction without the need for the artificial redox mediator, which is not viable on a homogenous gold electrode. Chronoamperometric current behavior is demonstrated with various concentrations from 0.5 mM to 28 mM. In this research, the combination of enzyme immobilization and sensing surfaces on nanowire arrays has shown superior performance with regards to the sensitivity and response time.

Citation Download Citation

Hargsoon Yoon, Devesh Deshpande, Ritesh R. Chintakuntla, and Vijay K. Varadan "Enzyme electrodes immobilized on hetero-structured metallic nanowire array for glucose sensing", Proc. SPIE 6416, Biomedical Applications of Micro- and Nanoengineering III, 641608 (14 December 2006); https://doi.org/10.1117/12.695223

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