Optical clearing of human eye sclera under the action of glucose solution

Alexey N. Bashkatov; Elina A. Genina; Vyacheslav I. Kochubey; Anna A. Gavrilova; Tatyana G. Kamenskikh; Vladimir A. Galanzha; Valery V. Tuchin

doi:10.1117/12.741022

27 April 2007 Optical clearing of human eye sclera under the action of glucose solution

Alexey N. Bashkatov, Elina A. Genina, Vyacheslav I. Kochubey, Anna A. Gavrilova, Tatyana G. Kamenskikh, Vladimir A. Galanzha, Valery V. Tuchin

Author Affiliations +

Proceedings Volume 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII; 653515 (2007) https://doi.org/10.1117/12.741022
Event: Saratov Fall Meeting 2006, 2006, Saratov, Russian Federation

Abstract

We present experimental results of investigation of the optical properties of the human eye sclera controlled by administration of osmotically active chemical, such as 40%-glucose solution. Administration of the chemical agent induces diffusion of matter and as a result equalization of the refractive indices of collagen and ground material. Results of the experimental study of influence of the glucose solution on the absorption and scattering properties of human sclera are presented. In vitro reflectance and transmittance spectra of the human sclera samples were measured by commercially available spectrophotometer CARY-2415 in the spectral range from 400 to 1800 nm. The reduced scattering coefficient of human sclera samples is significantly decreased under action of the osmotical solution were demonstrated.

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Alexey N. Bashkatov, Elina A. Genina, Vyacheslav I. Kochubey, Anna A. Gavrilova, Tatyana G. Kamenskikh, Vladimir A. Galanzha, and Valery V. Tuchin "Optical clearing of human eye sclera under the action of glucose solution", Proc. SPIE 6535, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, 653515 (27 April 2007); https://doi.org/10.1117/12.741022

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