Photoacoustic spectroscopy of the expired air at a human respiratory pathology

B. G. Ageev; V. A. Kapitanov; Yu. N. Ponomarev; O. Yu. Nikiforova; A. I. Karapuzikov; I. V. Sherstov; L. I. Volkova; E. Yu. Djakova; L. V. Kapilevich; D. V. Kapitanova; Yu. V. Kistenev; N. A. Smotrova; V. A. Fokin; A. V. Plohotin; T. A. Berendeeva

doi:10.1117/12.724939

13 December 2006 Photoacoustic spectroscopy of the expired air at a human respiratory pathology

B. G. Ageev, V. A. Kapitanov, Yu. N. Ponomarev, O. Yu. Nikiforova, A. I. Karapuzikov, I. V. Sherstov, L. I. Volkova, E. Yu. Djakova, L. V. Kapilevich, D. V. Kapitanova, Yu. V. Kistenev, N. A. Smotrova, V. A. Fokin, A. V. Plohotin, T. A. Berendeeva

Author Affiliations +

Proceedings Volume 6580, 15th Symposium on High-Resolution Molecular Spectroscopy; 65800O (2006) https://doi.org/10.1117/12.724939
Event: 15th Symposium on High-Resolution Molecular Spectroscopy, 2006, Nizhny Novgorod, Russian Federation

Abstract

There are about 600 volatile compounds in air expired by man, including molecules-biomarkers of endogenous (produced in organism) origin, the specificity of generation and excretion mechanisms of which is sufficient for studies of both normal and pathologic processes. The goal of this work is analysis of the human-expired air by means of the intracavity laser photoacoustic sensor intended for detection of air gas admixtures having the absorption bands in the wavelength spectral range 9.2 - 10.8 μm. The sensor principle of operation is based on the photoacoustic effect caused by gas absorption of the CO₂ laser radiation. Measurements were conducted with a test group consisting of 100 persons and a group of patients (60 persons) affected by different bronchopulnionary pathologies. The state of health of each group members was determined from questioning data. The spectral absorption dependences were normalized to referent points and then investigated in respect to a qualitative coincidence. The typical results are presented below.

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B. G. Ageev, V. A. Kapitanov, Yu. N. Ponomarev, O. Yu. Nikiforova, A. I. Karapuzikov, I. V. Sherstov, L. I. Volkova, E. Yu. Djakova, L. V. Kapilevich, D. V. Kapitanova, Yu. V. Kistenev, N. A. Smotrova, V. A. Fokin, A. V. Plohotin, and T. A. Berendeeva "Photoacoustic spectroscopy of the expired air at a human respiratory pathology", Proc. SPIE 6580, 15th Symposium on High-Resolution Molecular Spectroscopy, 65800O (13 December 2006); https://doi.org/10.1117/12.724939

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