Texture in digital breast tomosynthesis: a comparison between mammographic and tomographic characterization of parenchymal properties

Despina Kontos; Predrag R. Bakic; Andrew D. A. Maidment

doi:10.1117/12.773144

17 March 2008 Texture in digital breast tomosynthesis: a comparison between mammographic and tomographic characterization of parenchymal properties

Despina Kontos, Predrag R. Bakic, Andrew D. A. Maidment

Author Affiliations +

Proceedings Volume 6915, Medical Imaging 2008: Computer-Aided Diagnosis; 69150A (2008) https://doi.org/10.1117/12.773144
Event: Medical Imaging, 2008, San Diego, California, United States

Abstract

Studies have demonstrated a relationship between mammographic texture and breast cancer risk. To date, texture analysis has been limited by tissue superimposition in mammography. Digital Breast Tomosynthesis (DBT) is a novel x-ray imaging modality in which 3D images of the breast are reconstructed from a limited number of source projections. Tomosynthesis alleviates the effect of tissue superimposition and offers the ability to perform tomographic texture analysis; having the potential to ultimately yield more accurate measures of risk. In this study, we analyzed texture in DBT and digital mammography (DM). Our goal was to compare tomographic versus mammographic texture characterization and evaluate the robustness of texture descriptors in reflecting characteristic parenchymal properties. We analyzed DBT and DM images from 40 women with recently detected abnormalities and/or previously diagnosed breast cancer. Texture features, previously shown to correlate with risk, were computed from the retroareolar region. We computed the texture correlation between (i) the DBT and DM, and (ii) between contralateral and ipsilateral breasts. The effect of the gray-level quantization on the observed correlations was investigated. Low correlation was detected between DBT and DM features. The correlation between contralateral and ipsilateral breasts was significant for both modalities, and overall stronger for DBT. We observed that the selection of the gray-level quantization algorithm affects the detected correlations. The strong correlation between contralateral and ipsilateral breasts supports the hypothesis that parenchymal properties appear to be inherent in an individual woman; the texture of the unaffected breast could potentially be used as a marker of risk.

Citation Download Citation

Despina Kontos, Predrag R. Bakic, and Andrew D. A. Maidment "Texture in digital breast tomosynthesis: a comparison between mammographic and tomographic characterization of parenchymal properties", Proc. SPIE 6915, Medical Imaging 2008: Computer-Aided Diagnosis, 69150A (17 March 2008); https://doi.org/10.1117/12.773144

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available