Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information

Andrzej Krol; Levon Vogelsang; Yao Lu; Yuesheng Xu; Xiaofei Hu; Lixin Shen; David Feiglin; Edward Lipson

doi:10.1117/12.813815

13 March 2009 Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information

Andrzej Krol, Levon Vogelsang, Yao Lu, Yuesheng Xu, Xiaofei Hu, Lixin Shen, David Feiglin, Edward Lipson

Proceedings Volume 7258, Medical Imaging 2009: Physics of Medical Imaging; 72585C (2009) https://doi.org/10.1117/12.813815
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

In order to improve reconstructed image quality, we investigated performance of OSEM mesh-domain SPECT reconstruction with explicit prior anatomical and physiological information that was used to perform accurate attenuation compensation. It was accomplished in the following steps: (i) Obtain anatomical and physiological atlas of desired region of interest; (ii) Generate mesh that encodes properties of the atlas; (iii) Perform initial pixel-based reconstruction on projection dataset; (iv) Register the expected emission atlas to the initial pixel-based reconstruction and apply resulting transformation to meshed atlas; (v) Perform reconstruction in mesh-domain using deformed mesh of the atlas. This approach was tested on synthetic SPECT noise-free and noisy data. Comparative quantitative analysis demonstrated that this method outperformed pixel-based OSEM with uniform AC and is a promising approach that might lead to improved SPECT reconstruction quality.

Citation Download Citation

Andrzej Krol, Levon Vogelsang, Yao Lu, Yuesheng Xu, Xiaofei Hu, Lixin Shen, David Feiglin, and Edward Lipson "Implementation OSEM mesh-domain SPECT reconstruction with explicit prior information", Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 72585C (13 March 2009); https://doi.org/10.1117/12.813815

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
7 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Single photon emission computed tomography

Signal attenuation

Image quality

3D image reconstruction

Quantitative analysis

Data modeling

Image registration

Show All Keywords

Keywords/Phrases

Search In:

Publication Years