Low-power light and isolated rat hearts after ischemia of myocardium

Victor A. Monich; Olga V. Drugova; Valery F. Lazukin; Anna B. Bavrina

doi:10.1117/12.840841

25 February 2010 Low-power light and isolated rat hearts after ischemia of myocardium

Victor A. Monich, Olga V. Drugova, Valery F. Lazukin, Anna B. Bavrina

Proceedings Volume 7552, Mechanisms for Low-Light Therapy V; 75520E (2010) https://doi.org/10.1117/12.840841
Event: SPIE BiOS, 2010, San Francisco, California, United States

Abstract

Total ischemia of myocardium has been simulated on isolated hearts of rats. Effects of a low-power HeNe laser (λ=632.8 nm) and a fiber optic photo-luminescent radiation source of red light ( λ of the spectral peak is equal to 630 nm) on isolated heart contractile function characteristics and on lipid peroxidation (LPO) level in myocardium tissues have been investigated. Two groups of the specimens have been irradiated with red light during the postischemia (reperfusion) period of time. The first group has been treated with laser light and the second one with the luminescent radiation. More rapid restoration of the speed of contraction, of the force of contraction, of the relaxation speed and of the heart rate with respect to the data of the control group has been observed in both experimental groups. The similar tendency was observed in the laser treated specimens. The effects of fibrillation of myocardium of isolated hearts irradiated by lowpower He-Ne laser light were observed. These effects could be caused by the local light fluence rate excess in the interference pattern of laser light diffracted on the heart muscle structures.

Citation Download Citation

Victor A. Monich, Olga V. Drugova, Valery F. Lazukin, and Anna B. Bavrina "Low-power light and isolated rat hearts after ischemia of myocardium", Proc. SPIE 7552, Mechanisms for Low-Light Therapy V, 75520E (25 February 2010); https://doi.org/10.1117/12.840841

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