LCC demons with divergence term for liver MRI motion correction

Jihun Oh; Diego Martin; Oskar Skrinjar

doi:10.1117/12.843882

12 March 2010 LCC demons with divergence term for liver MRI motion correction

Jihun Oh, Diego Martin, Oskar Skrinjar

Proceedings Volume 7623, Medical Imaging 2010: Image Processing; 76232T (2010) https://doi.org/10.1117/12.843882
Event: SPIE Medical Imaging, 2010, San Diego, California, United States

Abstract

Contrast-enhanced liver MR image sequences acquired at multiple times before and after contrast administration have been shown to be critically important for the diagnosis and monitoring of liver tumors and may be used for the quantification of liver inflammation and fibrosis. However, over multiple acquisitions, the liver moves and deforms due to patient and respiratory motion. In order to analyze contrast agent uptake one first needs to correct for liver motion. In this paper we present a method for the motion correction of dynamic contrastenhanced liver MR images. For this purpose we use a modified version of the Local Correlation Coefficient (LCC) Demons non-rigid registration method. Since the liver is nearly incompressible its displacement field has small divergence. For this reason we add a divergence term to the energy that is minimized in the LCC Demons method. We applied the method to four sequences of contrast-enhanced liver MR images. Each sequence had a pre-contrast scan and seven post-contrast scans. For each post-contrast scan we corrected for the liver motion relative to the pre-contrast scan. Quantitative evaluation showed that the proposed method improved the liver alignment relative to the non-corrected and translation-corrected scans and visual inspection showed no visible misalignment of the motion corrected contrast-enhanced scans and pre-contrast scan.

Citation Download Citation

Jihun Oh, Diego Martin, and Oskar Skrinjar "LCC demons with divergence term for liver MRI motion correction", Proc. SPIE 7623, Medical Imaging 2010: Image Processing, 76232T (12 March 2010); https://doi.org/10.1117/12.843882

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