Nano-engineered materials based on fullerenes: synthesis and biomedical applications

Radu Claudiu Fierascu; Irina Dumitriu; Rodica Mariana Ion; Monica Neagu; Carolina Constantin; Crina Stavaru

doi:10.1117/12.882045

7 December 2010 Nano-engineered materials based on fullerenes: synthesis and biomedical applications

Radu Claudiu Fierascu, Irina Dumitriu, Rodica Mariana Ion, Monica Neagu, Carolina Constantin, Crina Stavaru

Proceedings Volume 7821, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies V; 78211J (2010) https://doi.org/10.1117/12.882045
Event: Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies, 2010, Constanta, Romania

Abstract

The nanoengineering of various materials for biomedical application has became in the last decade one of the most important research areas, due to the continuous struggle to find new and more efficient instruments for the therapy of cancer and other diseases. Attempts to obtain functionalized derivatives of fullerene seek the synthesis of watersoluble materials, in order to investigate their effects in physiological conditions. International studies on the biological properties of fullerenes and their derivatives, are now targeted towards anti-tumor effects, pharmacology and their involvement in oxidative stress. Their toxicity, demonstrated both in vitro and in vivo is important for characterization and selection of applications. Phototoxicity of some molecules of fullerenes has been identified as future therapeutic tool. The present paper describes the synthesis, characterization and some biomedical applications of some nanomaterials based on fullerenes.

Citation Download Citation

Radu Claudiu Fierascu, Irina Dumitriu, Rodica Mariana Ion, Monica Neagu, Carolina Constantin, and Crina Stavaru "Nano-engineered materials based on fullerenes: synthesis and biomedical applications", Proc. SPIE 7821, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies V, 78211J (7 December 2010); https://doi.org/10.1117/12.882045

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KEYWORDS

Fullerenes

Biomedical optics

Cell death

Absorption

Molecules

In vitro testing

Cancer

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