Spectrally-resolved imaging of dynamic turbid media

Nathan Hagen; Noah Bedard; Amaan Mazhar; Soren Konecky; Bruce J. Tromberg; Tomasz S. Tkaczyk

doi:10.1117/12.875406

10 February 2011 Spectrally-resolved imaging of dynamic turbid media

Nathan Hagen, Noah Bedard, Amaan Mazhar, Soren Konecky, Bruce J. Tromberg, Tomasz S. Tkaczyk

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Proceedings Volume 7892, Multimodal Biomedical Imaging VI; 789206 (2011) https://doi.org/10.1117/12.875406
Event: SPIE BiOS, 2011, San Francisco, California, United States

Abstract

We present a rapid, noncontact imaging technique which can obtain the spectrally- and spatially-resolved scattering and absorption coefficients of a turbid medium. The measurement involves combining a spatially modulated illumination pattern with a snapshot imaging spectrometer for measurement. After capture of an (x, y, λ) datacube, an image demodulation scheme is applied in post-processing to obtain the spatial maps of diffuse reflectance, absorption coefficient, and reduced scattering coefficient. The resulting system is used to dynamic maps (in 1 s intervals) of the brain's intrinsic optical signal.

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Nathan Hagen, Noah Bedard, Amaan Mazhar, Soren Konecky, Bruce J. Tromberg, and Tomasz S. Tkaczyk "Spectrally-resolved imaging of dynamic turbid media", Proc. SPIE 7892, Multimodal Biomedical Imaging VI, 789206 (10 February 2011); https://doi.org/10.1117/12.875406

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