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10 October 2012 DNA nano-circuit for electronics
Naoya Ogata
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Proceedings Volume 8464, Nanobiosystems: Processing, Characterization, and Applications V; 846403 (2012) https://doi.org/10.1117/12.930918
Event: SPIE NanoScience + Engineering, 2012, San Diego, California, United States
Abstract
This paper describes preparations of nano-scale patterned electric circuit based on high purity DNA molecules which are obtained from Salmon roe. The patterning on silicon substrate was carried out by an ink-jet method of aqueous solution of DNA. However, the Salmon-based DNA has a so huge molecular weight of over billions that even only 1wt% aqueous solution of DNA becomes gel without any fluidity. So, it is necessary to reduce molecular weights of DNA to increase fluidity of the aqueous solution of DNA, keeping the characteristic feature of double helical structures of DNA molecules to form metal-chlating complexes with various metal cations such as silver or copper cations. Several methods to reduce the molecular weight of DNA, including hydrolytic , enzymatic degradations and ultra-sonification. It was found that the best method to reduce the molecular weights (MW) of DNA was an enzymatic degradation of DNA to increase fluidity, thus being able to apply an ink-jet method for nano-scale patterning on a silicon wafer to form DNA circuit, followed by ion-crosslinking of DNA by dipping the patterned DNA circuit into aqueous solution of copper chloride. The DNA-CuCl2 patterned circuit was reduced to copper nano-lines for electric circuit, by using hydrazine as a reducing agent. Thus, all DNA devices can be prepared by the combination of DNA transistor and circuit.
© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
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Naoya Ogata "DNA nano-circuit for electronics", Proc. SPIE 8464, Nanobiosystems: Processing, Characterization, and Applications V, 846403 (10 October 2012); https://doi.org/10.1117/12.930918
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KEYWORDS
Copper
Molecules
Semiconducting wafers
Silicon
Electronics
Bioalcohols
Ions
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