Nucleotide fluctuation in extremophilic cold-adapted sequences and their degradation codes

George Tremberger Jr.; S. Dehipawala; E. Cheung; Jesaiah Prayor; Rafael Duran; P. Schneider; D. Lieberman; T. Holden; T. Cheung

doi:10.1117/12.929653

15 October 2012 Nucleotide fluctuation in extremophilic cold-adapted sequences and their degradation codes

George Tremberger Jr., S. Dehipawala, E. Cheung, Jesaiah Prayor, Rafael Duran, P. Schneider, D. Lieberman, T. Holden, T. Cheung

Author Affiliations +

Proceedings Volume 8521, Instruments, Methods, and Missions for Astrobiology XV; 85210J (2012) https://doi.org/10.1117/12.929653
Event: SPIE Optical Engineering + Applications, 2012, San Diego, California, United States

Abstract

Extremophilic cold-adapted sequences and their degradation codes have been studied using fractal dimension and Shannon entropy. The nucleotide fluctuation of a DNA and/or RNA sequence can be studied as a random series using the nucleotide atomic number differences between A, T, C, G, and U. Studies of degradation codes suggest a positive correlation of Shannon entropy with mRNA stability, and a negative correlation of fractal dimension with mRNA stability.

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George Tremberger Jr., S. Dehipawala, E. Cheung, Jesaiah Prayor, Rafael Duran, P. Schneider, D. Lieberman, T. Holden, and T. Cheung "Nucleotide fluctuation in extremophilic cold-adapted sequences and their degradation codes", Proc. SPIE 8521, Instruments, Methods, and Missions for Astrobiology XV, 85210J (15 October 2012); https://doi.org/10.1117/12.929653

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