Analysis of the absorption spectra of gas emission of patients with lung cancer and chronic obstructive pulmonary disease by laser optoacoustic spectroscopy

Ekaterina B. Bukreeva; Anna A. Bulanova; Yurii V. Kistenev; Dmitry A. Kuzmin; Sergei A. Tuzikov; Evgenii L. Yumov

doi:10.1117/12.2016933

26 February 2013 Analysis of the absorption spectra of gas emission of patients with lung cancer and chronic obstructive pulmonary disease by laser optoacoustic spectroscopy

Ekaterina B. Bukreeva, Anna A. Bulanova, Yurii V. Kistenev, Dmitry A. Kuzmin, Sergei A. Tuzikov, Evgenii L. Yumov

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Proceedings Volume 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV; 86990K (2013) https://doi.org/10.1117/12.2016933
Event: Saratov Fall Meeting and Workshop on Laser Physics and Photonics 2012, 2012, Saratov, Russian Federation

Abstract

It is important to identify patients with chronic obstructive pulmonary disease (COPD) and lung cancer in the early stages of the disease. The method of laser opto-acoustic gas analysis, in this case, can act as a promising tool for diagnostics.

The material for this study were the gas emission samples collected from patients and healthy volunteers – samples of exhaled air, swabs from teeth and cheeks. A set of material was formed three groups: healthy volunteers, patients with COPD, lung cancer patients.

The resulting samples were analyzed by means of laser opto-acoustic gas analyzers: with intracavity location detector (ILPA-1), with extracavity location detector (LGA-2). Presentation of the results in an easy to visual form was performed using the method of elastic maps, based on the principal component analysis.

The results of analysis show potentialities of usage of laser optoacoustic spectroscopy application to assess the status of patients with chronic obstructive pulmonary disease and lung cancer.

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Ekaterina B. Bukreeva, Anna A. Bulanova, Yurii V. Kistenev, Dmitry A. Kuzmin, Sergei A. Tuzikov, and Evgenii L. Yumov "Analysis of the absorption spectra of gas emission of patients with lung cancer and chronic obstructive pulmonary disease by laser optoacoustic spectroscopy", Proc. SPIE 8699, Saratov Fall Meeting 2012: Optical Technologies in Biophysics and Medicine XIV; and Laser Physics and Photonics XIV, 86990K (26 February 2013); https://doi.org/10.1117/12.2016933

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