Venous saturation and blood flow behavior during laser-induced photodissociation of oxyhemoglobin

S. A. Mamilov; S. S. Yesman; M. M. Asimov; A. I. Gisbrecht

doi:10.1117/12.2013418

15 March 2013 Venous saturation and blood flow behavior during laser-induced photodissociation of oxyhemoglobin

S. A. Mamilov, S. S. Yesman, M. M. Asimov, A. I. Gisbrecht

Proceedings Volume 8770, 17th International School on Quantum Electronics: Laser Physics and Applications; 877018 (2013) https://doi.org/10.1117/12.2013418
Event: Seventeenth International School on Quantum Electronics: Laser Physics and Applications, 2012, Nessebar, Bulgaria

Abstract

The value of relative oxyhemoglobin concentration (saturation) in arterial (SаO₂) and venous blood (SvO₂) plays a significant role in the oxygen exchange in tissue and is used as criterion of delivery of oxygen adequate to the needs of tissue cells. Reduction of the volume of blood flows as well as reduction of oxygen concentration in arterial blood causes hypoxia - deficit of oxygen in tissue. One of the main mechanisms of elimination of hypoxia is based on compensation of the oxygen deficit by increasing the oxygen extraction from arterial blood, which leads to reduction of oxygen in the venous blood ¹. In this report two optical techniques for measurement of venous blood saturation are presented. The first one is based on the pulseoximetry with artificial mechanical modulation of the tissue volume and the second one on the spectrophotometry of human respiratory rhythm. Good correlation between the results obtained with both techniques is observed.

Citation Download Citation

S. A. Mamilov, S. S. Yesman, M. M. Asimov, and A. I. Gisbrecht "Venous saturation and blood flow behavior during laser-induced photodissociation of oxyhemoglobin", Proc. SPIE 8770, 17th International School on Quantum Electronics: Laser Physics and Applications, 877018 (15 March 2013); https://doi.org/10.1117/12.2013418

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