Portable multispectral imaging system for oral cancer diagnosis

Yao-Fang Hsieh; Mang Ou-Yang; Cheng-Chung Lee

doi:10.1117/12.2023304

28 September 2013 Portable multispectral imaging system for oral cancer diagnosis

Yao-Fang Hsieh, Mang Ou-Yang, Cheng-Chung Lee

Proceedings Volume 8845, Ultrafast Imaging and Spectroscopy; 884515 (2013) https://doi.org/10.1117/12.2023304
Event: SPIE Optical Engineering + Applications, 2013, San Diego, California, United States

Abstract

This study presents the portable multispectral imaging system that can acquire the image of specific spectrum in vivo for oral cancer diagnosis. According to the research literature, the autofluorescence of cells and tissue have been widely applied to diagnose oral cancer. The spectral distribution is difference for lesions of epithelial cells and normal cells after excited fluorescence. We have been developed the hyperspectral and multispectral techniques for oral cancer diagnosis in three generations. This research is the third generation. The excited and emission spectrum for the diagnosis are acquired from the research of first generation. The portable system for detection of oral cancer is modified for existing handheld microscope. The UV LED is used to illuminate the surface of oral cavity and excite the cells to produce fluorescent. The image passes through the central channel and filters out unwanted spectrum by the selection of filter, and focused by the focus lens on the image sensor. Therefore, we can achieve the specific wavelength image via fluorescence reaction. The specificity and sensitivity of the system are 85% and 90%, respectively.

Citation Download Citation

Yao-Fang Hsieh, Mang Ou-Yang, and Cheng-Chung Lee "Portable multispectral imaging system for oral cancer diagnosis", Proc. SPIE 8845, Ultrafast Imaging and Spectroscopy, 884515 (28 September 2013); https://doi.org/10.1117/12.2023304

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