Application of OCT elastography for diagnosis of thyroid hydatoncus

Zhifang Li; Xiaona Lin; Hui Li; Wei R. Chen

doi:10.1117/12.2038102

28 February 2014 Application of OCT elastography for diagnosis of thyroid hydatoncus

Zhifang Li, Xiaona Lin, Hui Li, Wei R. Chen

Author Affiliations +

Proceedings Volume 8944, Biophotonics and Immune Responses IX; 89440N (2014) https://doi.org/10.1117/12.2038102
Event: SPIE BiOS, 2014, San Francisco, California, United States

Abstract

In this study, we presented a method combining optical coherence tomography with wavelet differentiation method to quantify the elastic properties of tissue. Based on the optimized kernel size for 2D normalized cross-correlation, the wavelet differentiation method was used to estimate the tissue strains. The influences of the dilation parameter of wavelet on calculations of axial strain had been investigated. Experimental results suggest that the dilation parameter of 8 was selected in strain calculation for best quality of axial strain images. The method based on wavelet differentiation shows great potential for optical coherence tomography elastography. In addition, elastic properties images of thyroid with suspected cysts were depicted to distinguish benign lesions qualitatively. Thus, elastic properties imaging based on optical coherence elastography shows great promise for the detailed characterization of lesions and preliminary diagnosis of human thyroid diseases.

Citation Download Citation

Zhifang Li, Xiaona Lin, Hui Li, and Wei R. Chen "Application of OCT elastography for diagnosis of thyroid hydatoncus", Proc. SPIE 8944, Biophotonics and Immune Responses IX, 89440N (28 February 2014); https://doi.org/10.1117/12.2038102

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