Method of azimuthally stable Mueller-matrix diagnostics of blood plasma polycrystalline films in cancer diagnostics

Yu. A. Ushenko; V. P. Prysyazhnyuk; M. S. Gavrylyak; M. P. Gorsky; V. T. Bachinskiy; O. Ya. Vanchuliak

doi:10.1117/12.2072273

20 February 2015 Method of azimuthally stable Mueller-matrix diagnostics of blood plasma polycrystalline films in cancer diagnostics

Yu. A. Ushenko, V. P. Prysyazhnyuk, M. S. Gavrylyak, M. P. Gorsky, V. T. Bachinskiy, O. Ya. Vanchuliak

Author Affiliations +

Proceedings Volume 9258, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies VII; 925807 (2015) https://doi.org/10.1117/12.2072273
Event: Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies 2014, 2014, Constanta, Romania

Abstract

A new information optical technique of diagnostics of the structure of polycrystalline films of blood plasma is proposed. The model of Mueller-matrix description of mechanisms of optical anisotropy of such objects as optical activity, birefringence, as well as linear and circular dichroism is suggested. The ensemble of informationally topical azimuthally stable Mueller-matrix invariants is determined. Within the statistical analysis of such parameters distributions the objective criteria of differentiation of films of blood plasma taken from healthy and patients with liver cirrhosis were determined. From the point of view of probative medicine the operational characteristics (sensitivity, specificity and accuracy) of the information-optical method of Mueller-matrix mapping of polycrystalline films of blood plasma were found and its efficiency in diagnostics of liver cirrhosis was demonstrated. Prospects of application of the method in experimental medicine to differentiate postmortem changes of the myocardial tissue was examined.

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Yu. A. Ushenko, V. P. Prysyazhnyuk, M. S. Gavrylyak, M. P. Gorsky, V. T. Bachinskiy, and O. Ya. Vanchuliak "Method of azimuthally stable Mueller-matrix diagnostics of blood plasma polycrystalline films in cancer diagnostics ", Proc. SPIE 9258, Advanced Topics in Optoelectronics, Microelectronics, and Nanotechnologies VII, 925807 (20 February 2015); https://doi.org/10.1117/12.2072273

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