Microvascular changes during acne lesion initiation and scarring within human skin is revealed in vivo using optical microangiography

Utku Baran; Yuandong Li; Woo J. Choi; Ruikang K. Wang

doi:10.1117/12.2082717

26 February 2015 Microvascular changes during acne lesion initiation and scarring is revealed in vivo using optical microangiography

Utku Baran, Yuandong Li, Woo J. Choi, Ruikang K. Wang

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Proceedings Volume 9303, Photonic Therapeutics and Diagnostics XI; 93030J (2015) https://doi.org/10.1117/12.2082717
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Acne is a common skin disease in society and often leads to scarring. In this paper, we demonstrate the capabilities of swept-source optical coherence tomography (SS-OCT) in detecting specific features of acne lesion initiation and scarring on human facial skin in vivo over 30 days. Optical microangiography (OMAG) technique made it possible to image 3D tissue microvasculature changes up to 1 mm depth in vivo without the need of exogenous contrast agents in ~10 seconds. The presented results show promise to facilitate clinical trials of treatment and prognosis of acne vulgaris by detecting cutaneous microvasculature and structural changes within human skin in vivo.

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Utku Baran, Yuandong Li, Woo J. Choi, and Ruikang K. Wang "Microvascular changes during acne lesion initiation and scarring is revealed in vivo using optical microangiography", Proc. SPIE 9303, Photonic Therapeutics and Diagnostics XI, 93030J (26 February 2015); https://doi.org/10.1117/12.2082717

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KEYWORDS

Skin

In vivo imaging

Tissue optics

Optical coherence tomography

3D image processing

Imaging systems

Tissues

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