Using a reflectance-based correction on Cherenkov images to strengthen correlation with radiation surface dose in an anthropomorphic breast phantom

Jacqueline M. Andreozzi; Rongxiao Zhang; Adam K. Glaser; David J. Gladstone; Lesley A. Jarvis; Brian W. Pogue

doi:10.1117/12.2212648

29 February 2016 Using a reflectance-based correction on Cherenkov images to strengthen correlation with radiation surface dose in an anthropomorphic breast phantom

Jacqueline M. Andreozzi, Rongxiao Zhang, Adam K. Glaser, David J. Gladstone, Lesley A. Jarvis, Brian W. Pogue

Author Affiliations +

Proceedings Volume 9689, Photonic Therapeutics and Diagnostics XII; 968941 (2016) https://doi.org/10.1117/12.2212648
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Cherenkov imaging during radiotherapy is a method by which an optical analog for the high-energy radiation beam can be observed directly on the surface of the patient. While simple geometries and volumes demonstrate a strong correlation between Cherenkov emission intensity and surface dose, in vivo data collected from 14 whole-breast patients has not exhibited the same correlation. The purpose of this anthropomorphic phantom study was to investigate a new method for improving the in vivo correlation based on a pixel-by-pixel correction from a reference reflectance image. The pixel intensities in Cherenkov images of a phantom were correlated with the surface dose measured from thermoluminescent dosimeters (TLDs) placed on the phantom’s surface. Because the phantom had homogeneous optical properties, results show a no appreciable change in correlation between Cherenkov intensity and surface dose when using the correction method on images of an anthropomorphic solid silicone phantom, nor a change in the dose fall-off at the edges of the phantom. The method may improve correlation with in vivo data.

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Jacqueline M. Andreozzi, Rongxiao Zhang, Adam K. Glaser, David J. Gladstone, Lesley A. Jarvis, and Brian W. Pogue "Using a reflectance-based correction on Cherenkov images to strengthen correlation with radiation surface dose in an anthropomorphic breast phantom", Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 968941 (29 February 2016); https://doi.org/10.1117/12.2212648

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