Non-invasive chemically-selective Raman signal enhancement in a scattering medium

Bingxin Tian; Bernhard Rauer; Antoine Boniface; Sylvain Gigan; Hilton Barbosa de Aguiar

doi:10.1117/12.2610087

2 March 2022 Non-invasive chemically-selective Raman signal enhancement in a scattering medium

Bingxin Tian, Bernhard Rauer, Antoine Boniface, Sylvain Gigan, Hilton Barbosa de Aguiar

Proceedings Volume PC11969, Adaptive Optics and Wavefront Control for Biological Systems VIII; PC1196906 (2022) https://doi.org/10.1117/12.2610087
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Deep Raman imaging in complex media has been elusive, due to scattering of the excitation light. Here, we exploit non-invasive wavefront shaping methods using a spectrally resolved speckle variance optimization algorithm in order to enhance the spontaneous Raman signals of a single particle. We demonstrate unprecedented signal enhancement (>5x) in a non-invasive manner for an epi geometry.

Conference Presentation

Citation Download Citation

Bingxin Tian, Bernhard Rauer, Antoine Boniface, Sylvain Gigan, and Hilton Barbosa de Aguiar "Non-invasive chemically-selective Raman signal enhancement in a scattering medium", Proc. SPIE PC11969, Adaptive Optics and Wavefront Control for Biological Systems VIII, PC1196906 (2 March 2022); https://doi.org/10.1117/12.2610087

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