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17 March 2023 Using spectroscopy to study skin conditions
Sunil Kalia, Haishan Zeng, Tashmeeta Ahad, Jianhua Zhao, Harvey Lui
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Proceedings Volume PC12352, Photonics in Dermatology and Plastic Surgery 2023; PC123520A (2023) https://doi.org/10.1117/12.2657459
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
Inflammatory skin diseases affect a large proportion of the population, for instance the prevalence of eczema is 20%. However, objective disease measurements to assess severity are lacking for this common inflammatory skin condition. In this study, we assess the use of a non-invasive optical method to characterize different biomarkers in eczema patients. Raman spectroscopy which measures molecular bond vibrations was used to assess different disease characteristics including keratin, ceramide, protein and water content. Eczema patients showed a lower amount of lipid content (eg. ceramides), and asymmetric protein and bound water. These findings will be further explored to correlate with disease severity.
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Sunil Kalia, Haishan Zeng, Tashmeeta Ahad, Jianhua Zhao, and Harvey Lui "Using spectroscopy to study skin conditions", Proc. SPIE PC12352, Photonics in Dermatology and Plastic Surgery 2023, PC123520A (17 March 2023); https://doi.org/10.1117/12.2657459
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KEYWORDS
Skin
Raman spectroscopy
Spectroscopy
Proteins
Molecular spectroscopy
Neck
Optical inspection
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