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17 March 2023 A minimally invasive tethered capsule endomicroscopy and biopsy platform
Andrew D. Thrapp, Rachel Shore, Tyler Rhim, David Otuya, Tara Lignelli, Matt Beatty, Rachel Smith, Gary Tearney
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Proceedings Volume PC12356, Endoscopic Microscopy XVIII; PC123560I (2023) https://doi.org/10.1117/12.2650048
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
OCT-based tethered capsule endomicroscopy (TCE) is an emerging tool for unsedated Barrett’s Esophagus (BE) screening. Cancer progression risk is best determined by acquiring and analyzing a BE tissue sample. We report a TCE device with a biopsy channel capable of extracting tissue samples in an unsedated platform. We show in swine studies (n=2) the biopsy capsule can locate simulated targets and visualize the extraction of biopsies. Owing to its capacity to be utilized in patients without requiring sedation, this new technology could be useful for screening for BE subjects who have an elevated risk of developing cancer.
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Andrew D. Thrapp, Rachel Shore, Tyler Rhim, David Otuya, Tara Lignelli, Matt Beatty, Rachel Smith, and Gary Tearney "A minimally invasive tethered capsule endomicroscopy and biopsy platform", Proc. SPIE PC12356, Endoscopic Microscopy XVIII, PC123560I (17 March 2023); https://doi.org/10.1117/12.2650048
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KEYWORDS
Biopsy
Endomicroscopy
Optical coherence tomography
Tissues
Cancer
In vivo imaging
Esophagus
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