Coarse-scale optoretinography (CoORG) with a line-scan OCT for extended field-of-view

Teng Liu; Xiaoyun Jiang; Vimal Prabhu Pandiyan; Emily Slezak; Ramkumar Sabesan

doi:10.1117/12.2650451

17 March 2023 Coarse-scale optoretinography (CoORG) with a line-scan OCT for extended field-of-view

Teng Liu, Xiaoyun Jiang, Vimal Prabhu Pandiyan, Emily Slezak, Ramkumar Sabesan

Proceedings Volume PC12360, Ophthalmic Technologies XXXIII; PC123600E (2023) https://doi.org/10.1117/12.2650451
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Optoretinography serves as an effective biomarker for light-evoked retinal activity owing to its sensitive, objective, and precise localization of retinal function and dysfunction. We developed a coarse-scale optoretinography instrument based on a line-scan spectral domain OCT. We demonstrate its ability to acquire robust and repeatable ORG signals rapidly over a 5° field of view in a single acquisition, without adaptive optics. The high repeatability, good agreement with cellular-scale ORGs, and non-AO operation are of promise for its widespread clinical application to retinal diseases such as AMD and inherited retinal degenerations.

Conference Presentation

Citation Download Citation

Teng Liu, Xiaoyun Jiang, Vimal Prabhu Pandiyan, Emily Slezak, and Ramkumar Sabesan "Coarse-scale optoretinography (CoORG) with a line-scan OCT for extended field-of-view", Proc. SPIE PC12360, Ophthalmic Technologies XXXIII, PC123600E (17 March 2023); https://doi.org/10.1117/12.2650451

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