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With the rise in minimally invasive surgery and machine learning, there are emerging opportunities to improve patient outcomes with endoscopic techniques that quantify tissue shape and optical properties. We introduce a speckle-illumination stereo endoscope (SSE) that utilizes structured illumination to enhance both depth and optical property mapping. An SSE prototype was constructed and applied to fresh pig colon samples. SSE-estimated depth and optical property maps compare favorably to gold standard techniques. Requiring only minor modifications to existing commercial stereoscopes, the SSE could provide surgeons with improved visual depth perception and maps of biomarkers in vivo.
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Anthony A. Song, Mason T. Chen, Nicholas J. Durr, "Speckle-illumination stereo endoscopy for depth and optical property mapping," Proc. SPIE PC12361, Molecular-Guided Surgery: Molecules, Devices, and Applications IX, PC1236103 (17 March 2023); https://doi.org/10.1117/12.2650639