Radiometric characterization methods for fluorescence guidance imaging systems using a calibrated solid-state emitter

Alberto J. Ruiz; Edwin Robledo; Eammon Littler; Ethan P. M. LaRochelle

doi:10.1117/12.2667824

6 March 2023 Radiometric characterization methods for fluorescence guidance imaging systems using a calibrated solid-state emitter

Alberto J. Ruiz, Edwin Robledo, Eammon Littler, Ethan P. M. LaRochelle

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Proceedings Volume PC12370, Design and Quality for Biomedical Technologies XVI; PC123700B (2023) https://doi.org/10.1117/12.2667824
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

The emerging clinical use of fluorescent agents has led to a shift in intraoperative imaging practices that overcome the limitations of human vision, thereby improving treatment outcomes in applications such as perfusion assessment and positive margins in tumor resection. As the field of fluorescence-guided surgery (FGS) expands, there is a wider range of imaging systems that are indicated for the same uses, such that there is a compelling need for standards and methods that enable system characterization and intersystem comparisons. Here we present methods for the radiometric characterization of FGS imaging systems using a calibrated solid-state emitter to enable the conversion of imager-specific responses to SI-traceable units.

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Alberto J. Ruiz, Edwin Robledo, Eammon Littler, and Ethan P. M. LaRochelle "Radiometric characterization methods for fluorescence guidance imaging systems using a calibrated solid-state emitter", Proc. SPIE PC12370, Design and Quality for Biomedical Technologies XVI, PC123700B (6 March 2023); https://doi.org/10.1117/12.2667824

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KEYWORDS

Imaging systems

Fluorescence

Radiometric calibration

Solid state physics

Solid state electronics

Perfusion imaging

Resection

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