Quantitative deep tissue diffuse optical spectroscopy and imaging

Thomas D. O'Sullivan

doi:10.1117/12.2649023

17 March 2023 Quantitative deep tissue diffuse optical spectroscopy and imaging

Thomas D. O'Sullivan

Proceedings Volume PC12430, Quantum Sensing and Nano Electronics and Photonics XIX; PC1243012 (2023) https://doi.org/10.1117/12.2649023
Event: SPIE OPTO, 2023, San Francisco, California, United States

Abstract

Though near-infrared spectroscopy (NIRS) has been used to noninvasively measure human physiology for over 40 years, most NIRS devices ignore spatial and temporal variations in tissue optical scattering. Alternatively, temporally and spatially-resolved NIRS, in either the real or frequency domains, allows for direct measurements of tissue optical scattering and thus the ability to make direct measurements of tissue composition and oxygen metabolism. In this tutorial presentation, I will give an overview of the technology and applications of quantitative deep tissue optical spectroscopy, with a focus on how new photonics technologies are improving the performance and accessibility of these techniques.

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Thomas D. O'Sullivan "Quantitative deep tissue diffuse optical spectroscopy and imaging", Proc. SPIE PC12430, Quantum Sensing and Nano Electronics and Photonics XIX, PC1243012 (17 March 2023); https://doi.org/10.1117/12.2649023

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KEYWORDS

Tissue optics

Imaging spectroscopy

Diffuse optical spectroscopy

Diffuse optical imaging

Near infrared spectroscopy

Optical imaging

Optical testing

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