Exploring tape-stripping and supercontinuum-based optical coherence tomography for diagnosing malignant melanoma skin cancer

Niels M. Israelsen; Terese von Knorring; Silje Mai Wachs; Coraline Lapre; Christian R. Petersen; Mette Mogensen; Ole Bang

doi:10.1117/12.2692227

13 March 2024 Exploring tape-stripping and supercontinuum-based optical coherence tomography for diagnosing malignant melanoma skin cancer

Niels M. Israelsen, Terese von Knorring, Silje Mai Wachs, Coraline Lapre, Christian R. Petersen, Mette Mogensen, Ole Bang

Author Affiliations +

Proceedings Volume PC12816, Photonics in Dermatology and Plastic Surgery 2024; PC128160Q (2024) https://doi.org/10.1117/12.2692227
Event: SPIE BiOS, 2024, San Francisco, California, United States

Conference Poster

Abstract

Both new and established technologies are explored in the pursuit of finding an efficient approach for diagnosing malignant melanoma skin cancer. The non-invasive sub-surface imaging technique of optical coherence tomography (OCT) is frequently applied in the ophthalmological clinic, but is still emerging within the field of dermatology. We present our work in testing two supercontinuum OCT systems for characterizing tape strips applied to skin cancer patients. Tape strips were collected in a clinical trial of 75 skin cancer patients at Bispebjerg Hospital, Denmark. After low-temperature storage, samples were scanned by a near-infrared OCT system and a mid-infrared OCT system of wavelengths 1.3 µm and 4 µm. We report on the scanning protocol and how the wavelength dependent OCT scans can be interpreted in order to target malignant melanoma characteristics.

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Niels M. Israelsen, Terese von Knorring, Silje Mai Wachs, Coraline Lapre, Christian R. Petersen, Mette Mogensen, and Ole Bang "Exploring tape-stripping and supercontinuum-based optical coherence tomography for diagnosing malignant melanoma skin cancer", Proc. SPIE PC12816, Photonics in Dermatology and Plastic Surgery 2024, PC128160Q (13 March 2024); https://doi.org/10.1117/12.2692227

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