PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
Retinal vascular impairments, including reduced functional responsiveness, are implicated in a number of prevalent retinal disorders. Improved depth-resolved retinal vasculature imaging is possible using optical coherence tomography angiography (OCTA) after injection of a contrast agent. Flicker stimulated OCTA imaging on C57BL/6 healthy mice was performed to evaluate functional response and vascular connections with and without additional contrast. Major retinal vessels showed an increase in vessel diameter that was more pronounced in a mouse with contrast injection than in one without. Additionally, a contrast-injected mouse showed 6 times more connecting vessels overall. Contrast-enhanced OCTA may improve quantification of hemodynamics in animal models of disease.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.