Multiple scattering suppression for in vivo OCT measurement by B-scan-wise-multi-focus averaging method

Yiqiang Zhu; Lida Zhu; Shuichi Makita; Yiheng Lim; Yu Guo; Yoshiaki Yasuno

doi:10.1117/12.3003699

13 March 2024 Multiple scattering suppression for in vivo OCT measurement by B-scan-wise-multi-focus averaging method

Yiqiang Zhu, Lida Zhu, Shuichi Makita, Yiheng Lim, Yu Guo, Yoshiaki Yasuno

Proceedings Volume PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII; PC1283013 (2024) https://doi.org/10.1117/12.3003699
Event: SPIE BiOS, 2024, San Francisco, California, United States

Conference Poster

Abstract

We propose a B-scan-wise- multi-focus average method (B-MFA) to suppress multiple scattering noise for in-vivo imaging. This method uses only multiple B-scans with modulated focus position for complex averaging, and a one-dimensional computational refocusing is applied to cancel the defocus in each B-scan. To validate the proposed method, ten medaka fish were measured in-vivo without anesthesia. The results show that B-MFA can enhance the OCT image contrast in the deep regions.

Citation Download Citation

Yiqiang Zhu, Lida Zhu, Shuichi Makita, Yiheng Lim, Yu Guo, and Yoshiaki Yasuno "Multiple scattering suppression for in vivo OCT measurement by B-scan-wise-multi-focus averaging method", Proc. SPIE PC12830, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVIII, PC1283013 (13 March 2024); https://doi.org/10.1117/12.3003699

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