Multispectral photoacoustic microscopy with a single-shot 20 kHz tunable Ti:sapphire laser

Thanh Dat Le; Yong-Jae Lee; Tae Joong Eom; Changho Lee

doi:10.1117/12.3002176

13 March 2024 Multispectral photoacoustic microscopy with a single-shot 20 kHz tunable Ti:sapphire laser

Thanh Dat Le, Yong-Jae Lee, Tae Joong Eom, Changho Lee

Proceedings Volume PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024; PC128422K (2024) https://doi.org/10.1117/12.3002176
Event: SPIE BiOS, 2024, San Francisco, California, United States

Conference Poster

Abstract

Photoacoustic microscopy (PAM) allows for the visualization of microscale structures and functionalities by detecting various chromophores in biological tissues based on their absorption spectra at specific laser wavelengths. PAM differentiates oxy and deoxy blood, water, collagen, and lipid with unique absorption spectra in NIR. To enhance the functionality of PAM, integrating multi-wavelength laser sources, particularly Ti:Sapphire lasers, is gaining significant attention. Ti:Sapphire lasers are considered an advanced solution due to their high energy efficiency and wavelength tunability. This presentation introduces a single-shot, wavelength-tunable Ti:Sapphire-based multispectral PAM system capable of rapidly performing functional imaging of blood concentrations and ICG-lymphography.

Citation Download Citation

Thanh Dat Le, Yong-Jae Lee, Tae Joong Eom, and Changho Lee "Multispectral photoacoustic microscopy with a single-shot 20 kHz tunable Ti:sapphire laser", Proc. SPIE PC12842, Photons Plus Ultrasound: Imaging and Sensing 2024, PC128422K (13 March 2024); https://doi.org/10.1117/12.3002176

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