Optical coherence tomography assisted motion-corrected Brillouin microscopy of skin in vivo

Maria Romodina; Kanwarpal Singh

doi:10.1117/12.3001483

13 March 2024 Optical coherence tomography assisted motion-corrected Brillouin microscopy of skin in vivo

Maria Romodina, Kanwarpal Singh

Proceedings Volume PC12844, Optical Elastography and Tissue Biomechanics XI; PC128440M (2024) https://doi.org/10.1117/12.3001483
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Biomechanical testing of human skin in vivo is important for studying the aging process and pathological conditions such as skin cancer. Brillouin microscopy allows non-contact measurements of the bulk elastic modulus of the skin, providing information on the mechanical properties of the tissue. Here, we use the combination of Brillouin microscopy and OCT imaging for motion-corrected, depth-resolved biomechanical testing of human skin in vivo. We found that the experimentally measured Brillouin frequency shift of the epidermis is higher than that of the dermis, indicating the higher stiffness of the upper skin layer.

Conference Presentation

Citation Download Citation

Maria Romodina and Kanwarpal Singh "Optical coherence tomography assisted motion-corrected Brillouin microscopy of skin in vivo", Proc. SPIE PC12844, Optical Elastography and Tissue Biomechanics XI, PC128440M (13 March 2024); https://doi.org/10.1117/12.3001483

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