Large-scale dynamic imaging by mesoscopic oblique plane microscopy and computational augmentation

Ji Yi

doi:10.1117/12.3012548

13 March 2024 Large-scale dynamic imaging by mesoscopic oblique plane microscopy and computational augmentation

Ji Yi

Proceedings Volume PC12857, Computational Optical Imaging and Artificial Intelligence in Biomedical Sciences; PC1285701 (2024) https://doi.org/10.1117/12.3012548
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

The recent years have witnessed a rapid growth of microscopic techniques for high-speed, large-scale imaging in biological systems. Biological structures are hierarchical and dynamic, which posts challenges to balance the field of view, imaging depth, resolution, speed, and SNR. In this talk, I will first introduce our recent efforts in developing mesoscopic oblique plane microscopy (Meso-OPM) to allow flexible tuning of the imaging scale/resolution, and then introduce the challenges and opportunities for computational augmentations to improve imaging quality, SNR and general image formation.

Conference Presentation

Citation Download Citation

Ji Yi "Large-scale dynamic imaging by mesoscopic oblique plane microscopy and computational augmentation", Proc. SPIE PC12857, Computational Optical Imaging and Artificial Intelligence in Biomedical Sciences, PC1285701 (13 March 2024); https://doi.org/10.1117/12.3012548

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