Presentation
11 June 2024 Folate-receptor-targeted NIR-active conjugated polymer nanoparticles
Author Affiliations +
Abstract
This work presents the conjugation of tumor-specific targeting ligands, folic acid, onto the surface of Conjugated Polymer Nanoparticles (CPNs) based on a common solar cell material (PTB7), which exhibits low nonspecific cell adhesion. The goal is to create near-infrared (NIR)-active theranostic probes capable of specifically targeting cancer cells. By adjusting the proportion of folic acid during the synthesis process, the targeting efficiency and singlet oxygen generation efficiency of the nanoparticles can be finely tuned.
Conference Presentation
© (2024) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Miao Zhao, Mark Green, Philip Manning, and Aliaksandra Rakovich "Folate-receptor-targeted NIR-active conjugated polymer nanoparticles", Proc. SPIE PC12991, Nanophotonics X, PC129911J (11 June 2024); https://doi.org/10.1117/12.3017049
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KEYWORDS
Photodynamic therapy

Tumors

Biomedical applications

Cancer

Near infrared

Radiotherapy

Resistance

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