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20 November 2017 Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo
Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski
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Journal of Biomedical Optics, Vol. 22, Issue 11, 110504 (November 2017). https://doi.org/10.1117/1.JBO.22.11.110504
Abstract
Mechanical pressure superficially applied on the human skin surface by a fiber-optic probe influences the spatial distribution of blood within the cutaneous tissues. Upon gradual load of weight on the probe, a stepwise increase in the skin reflectance spectra is observed. The decrease in the load follows the similar inverse staircase-like tendency. The observed stepwise reflectance spectra changes are due to, respectively, sequential extrusion of blood from the topical cutaneous vascular beds and their filling afterward. The obtained results are confirmed by Monte Carlo modeling. This implies that pressure-induced influence during the human skin diffuse reflectance spectra measurements in vivo should be taken into consideration, in particular, in the rapidly developing area of wearable gadgets for real-time monitoring of various human body parameters.
© 2017 Society of Photo-Optical Instrumentation Engineers (SPIE) 1083-3668/2017/$25.00 © 2017 SPIE
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Alexey P. Popov, Alexander V. Bykov, and Igor V. Meglinski "Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo," Journal of Biomedical Optics 22(11), 110504 (20 November 2017). https://doi.org/10.1117/1.JBO.22.11.110504
Received: 1 September 2017; Accepted: 27 October 2017; Published: 20 November 2017
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Cited by 24 scholarly publications and 2 patents.
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KEYWORDS
Skin
Blood
Reflectivity
In vivo imaging
Diffuse reflectance spectroscopy
Monte Carlo methods
Fiber optics
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