Open Access
29 March 2019 Single snapshot of optical properties image quality improvement using anisotropic two-dimensional windows filtering
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Abstract
Imaging methods permitting real-time, wide-field, and quantitative optical mapping of biological tissue properties offer an unprecedented range of applications for clinical use. Following the development of spatial frequency domain imaging, we introduce a real-time demodulation method called single snapshot of optical properties (SSOPs). However, since this method uses only a single image to generate absorption and reduced scattering maps, it was limited by a degraded image quality resulting in artifacts that diminished its potential for clinical use. We present filtering strategies for improving the image quality of optical properties maps obtained using SSOPs. We investigate the effect of anisotropic two-dimensional filtering strategies for spatial frequencies ranging from 0.1 to 0.4  mm  −  1 directly onto N  =  10 hands. Both accuracy and image quality of the optical properties are quantified in comparison with standard, multiple image acquisitions in the spatial frequency domain. Overall, using optimized filters, mean errors in predicting optical properties using SSOP remain under 8.8% in absorption and 7.5% in reduced scattering, while significantly improving image quality. Overall this work contributes to advance real-time, wide-field, and quantitative diffuse optical imaging toward clinical evaluation.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
Enagnon Aguénounon, Foudil Dadouche, Wilfried Uhring, and Sylvain Gioux "Single snapshot of optical properties image quality improvement using anisotropic two-dimensional windows filtering," Journal of Biomedical Optics 24(7), 071611 (29 March 2019). https://doi.org/10.1117/1.JBO.24.7.071611
Received: 18 September 2018; Accepted: 12 February 2019; Published: 29 March 2019
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CITATIONS
Cited by 14 scholarly publications.
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KEYWORDS
Image quality

Spatial frequencies

Optical properties

Image filtering

Absorption

Scattering

Optical filters

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