With the enhancement of technology, data security has become incredibly significant. Nowadays, images and vital information are used in real-time, and high throughput architecture is required for internet of things and real-time applications. We mainly focus on the high throughput architecture of PRINT cipher. PRINT cipher is a lightweight block cipher with a block size of 48-bit and 96-bit. Loop-unrolled, 48-bit pipelined, and 96-bit pipelined architectures are designed and implemented on different field programmable gate array and application-specific integrated circuit platforms. The maximum operating frequency obtained for 48-bit pipelined is 259.67 MHz on Virtex-4 and 310.67 MHz for 96-bit pipelined on Virtex-5. Finally, with the help of a controller, 48-bit high throughput pipelined architecture was utilized for image encryption of both grayscale and color images. The security analysis of encrypted images for color and grayscale images using PRINT cipher shows better performance and more robust protection against statistical, entropy, and differential attacks.