24 December 2021 Fast three-dimensional super-resolution photoacoustic microscopy imaging
Mohammadreza Amjadian, Seyed Masood Mostafavi, Zahra Kavehvash, Rahim Faez
Author Affiliations +
Abstract

We proposed a fast three-dimensional (3D) structured illumination photoacoustic microscopy (PAM). In the conventional PAM systems, the optical and acoustical beams need mechanical scanning to cover the whole area of interest for imaging imposing constraint on imaging speed. Using sinusoidal fringe illumination resulted in interference from a pair of tilted plane waves of different directions; capturing the resultant acoustic signal via a transducer array helped to improve lateral resolution and speed of the system while not degrading the depth-of-field (DOF). The sinusoidal structured illumination helps in more complete capture of spatial frequency components, which could be approved through a mathematical model of the system. Capturing more frequency components, in turn, results in improved frequency bandwidth and thus lateral resolution of the system. Simulation results show 5.4 dB improvements in image quality, based on the peak signal-to-noise ratio compared with a conventional structure.

© 2021 Society of Photo-Optical Instrumentation Engineers (SPIE) 0091-3286/2021/$28.00 © 2021 SPIE
Mohammadreza Amjadian, Seyed Masood Mostafavi, Zahra Kavehvash, and Rahim Faez "Fast three-dimensional super-resolution photoacoustic microscopy imaging," Optical Engineering 60(12), 123108 (24 December 2021). https://doi.org/10.1117/1.OE.60.12.123108
Received: 19 August 2021; Accepted: 9 December 2021; Published: 24 December 2021
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Cited by 1 scholarly publication.
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KEYWORDS
Image resolution

Imaging systems

Photoacoustic imaging

Monte Carlo methods

3D image processing

3D photoacoustic microscopy

Photoacoustic microscopy

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