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Ironizing radiation acoustic imaging (iRAI) is a novel imaging concept with the potential to map the radiation dose delivery in real time during external beam radiation therapy. In this study, iRAI volumetric dose mapping was achieved with 2D matrix transducer array using a C-shape 3D conformal treatment plan with clinically relevant setting and a moving beam plan in both phantoms and rabbit model in vivo. With the unique ability to map the volumetric dose delivery in real time, iRAI 3D dose mapping can be developed into a new tool for quantifying the accuracy of dose delivery of radiation therapy.
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Wei Zhang, Ibrahim Oraiqat, Kaiwei Chang, Noora Ba Sunbul, Dale Litzenberg, Kyle Cuneo, Paul Carson, Issam El Naqa, Xueding Wang, "Ionizing radiation acoustic imaging (iRAI) for volumetric dose mapping during external beam radiotherapy," Proc. SPIE PC11960, Photons Plus Ultrasound: Imaging and Sensing 2022, PC1196015 (7 March 2022); https://doi.org/10.1117/12.2608005