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Optical coherence tomography (OCT) is a popular noninvasive technique for obtaining depth-resolved information about tissue. By applying a windowing technique to the OCT interferogram, spectrum-dependent optical properties can be measured in order to identify tissue optical properties such as scattering attenuation coefficient and scattering power. By mapping the distinct ranges of these optical properties for different morphologies and stages of human colorectal adenoma tissues, rapid classification of disease is possible, potentially allowing for better identification of their malignant potential when performing surveillance colonoscopy.
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Wesley Y. Kendall, Julianna Bordas, Seyedbabak Mirminachi, Jatin Roper, Adam Wax, "Spectroscopic characterization of human colorectal adenoma using optical coherence tomography," Proc. SPIE PC11974, Biomedical Applications of Light Scattering XII, PC1197406 (3 March 2022); https://doi.org/10.1117/12.2607771